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References

Caspases

Los M, Stroh C, Janicke RU, Engels IH, Schulze-Osthoff K: Caspases: more than just killers?
Trends Immunol 2001, 22:31-34.

Algeciras-Schimnich A, Bamhart BC, Peter ME: Apoptosis-independent functions of killer caspases.
Curr Opin Cell Biol 2002, 14:721-726.

Launay S, Hermine O, Fontenay M, Kroemer G, Solary E, Garrido C: Vital functions for lethal caspases.
Oncogene 2005, 24:5137-5148.

Talanian RV, Quinlan C, Trautz S, Hackett MC, Mankovich JA, Banach D, Ghayur T, Brady KD, Wong WW: Substrate specificities of caspase family proteases.
J Biol Chem 1997, 272:9677-9682.

Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW: A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem 1997, 272:17907-17911.

Earnshaw WC, Martins LM, Kaufmann SH: Mammalian caspases: structure, activation, substrates, and functions during apoptosis.Annu Rev Biochem 1999, 68:383-424.

Fischer U, Janicke RU, Schulze-Osthoff K: Many cuts to ruin: a comprehensive ubdate of caspase substrates. Cell Death Differ 2003, 10:76-100.

 

Servers and related computational tools

Gasteiger E, Hoogland C, Gattiker A, Duvaud S, Wilkins MR, Appel RD, Bairoch A: Protein Identification and Analysis Tools on the ExPASy Server. In The Proteomics Protocols Handbook. Edited by: Walker JM. Humana Press; 2005:571-607.

Lohmuller T, Wenzler D, Hagemann S, Kiess W, Peters C, Dandekar T, Reinheckel T: Toward computer-based cleavage site prediction of cysteine endopeptidases. Biol Chem 2003, 384:899-909.

Garay-Malpartida HM, Occhiucci JM, Alves J, Belizario JE: CaSPredictor: a new computer-based tool for caspase substrate prediction. Bioinformatics 2005, 21(Suppl 1):i169-i176.

Backes C, Kuentzer J, Lenhof HP, Comtesse N, Meese E: GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences. Nucleic Acids Res 2005, 33:208-213.

Yang ZR: Prediction of caspase cleavage sites using Bayesian bio-basis function neural networks.
Bioinformatics 2005, 21:1831-1837.

 

Support Vector Machines

Byvatov E, Schneider G: Support vector machine applications in bioinformatics.
Appl Bioinformatics 2003, 2:67-77.

Chang CC, Lin CJ: LIBSVM: a library for support vector machines.
[http://www.csie.ntu.edu.tw/~cjlin/libsvm]

Burges CJC: A tutorial on support vector machines for pattern recognition.
Data Mining and Knowledge Discovery 1998, 2:121-167.